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If you haven't signed in with a AAAS ID before, you may need to set up a password now. Set Up Your Password. Even a 2°C drop in the core body temperature can cause hypothermia. At this point, the effects of cold on the brain are most apparent. "At 18°C, we'll have a massive leak in our blood-brain barrier, and the brain is not protected anymore from the normal junk we produce," Gracheva said. The resulting flood of toxins through the hole-ridden ... Authors and reviewers must have an account to sign into our Content Tracking System (CTS) at https://cts.sciencemag.org. If you do not have an account, you will need to create one by following the prompts on the welcome page. 5:55 PM ET. By Jon Cohen. A vaccine strategy aims to trigger production of multiple, powerful, "broadly neutralizing" antibodies (various colors) that can attach to different parts of HIV's surface protein (gray). Lars Hangartner & Christina Corbaci. 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